Hyperplasia

Hyperplasiaย (fromย ancient Greekย แฝ‘ฯ€ฮญฯย huperย 'over' + ฯ€ฮปฮฌฯƒฮนฯ‚ย plasisย 'formation'), orย hypergenesis, is an enlargement of an organ or tissue caused by an increase in the amount ofย organic tissueย that results fromย cell proliferation.[4|4]ย It may lead to theย gross enlargementย of an organ, and the term is sometimes confused with benignย neoplasiaย orย benign tumor.[5|5]

Hyperplasia is a common preneoplastic response to stimulus.[6|6]ย Microscopically, cells resemble normal cells but are increased in numbers. Sometimes cells may also be increased in size (hypertrophy).[7|7]ย Hyperplasia is different from hypertrophy in that theย adaptive cell changeย in hypertrophy is an increase in theย sizeย of cells, whereas hyperplasia involves an increase in theย numberย of cells.[8|8]